Inomata Challenging Lab developed the dry eye research app “Dry Eye Rhythm” in 2016 and continues to conduct digital cohort research.
Until now (October, 2024), we have published below papers:
1. Inomata T, Nakamura M, Iwagami M, Shiang T, Yoshimura Y, Fujimoto K, Okumura Y, Eguchi A, Iwata N, Miura M, Hori S, Hiratsuka Y, Uchino M, Tsubota K, Dana R, Murakami A. Risk Factors for Severe Dry Eye Disease: Crowdsourced Research Using DryEyeRhythm. Ophthalmology. 2019,126,766-768. (Ophthalmology, IF: 13.1)
2. Inomata T, Iwagami M, Nakamura M, Shiang T, Yoshimura Y, Fujimoto K, Okumura Y, Eguchi A, Iwata N, Miura M, Hori S, Hiratsuka Y, Uchino M, Tsubota K, Dana R, Murakami A. Characteristics and Risk Factors Associated With Diagnosed and Undiagnosed Symptomatic Dry Eye Using a Smartphone Application. JAMA Ophthalmol. 2020,138,58-68. (JAMA Ophthalmology, IF: 7.8)
3. Inomata T, Iwagami M, Nakamura M, Shiang T, Fujimoto K, Okumura Y, Iwata N, Fujio K, Hiratsuka Y, Hori S, Tsubota K, Dana R, Murakami A. Association between dry eye and depressive symptoms: Large-scale crowdsourced research using the DryEyeRhythm iPhone application. Ocul Surf. 2020,18,312-319. (Ocular Surface, IF: 5.9)
4. Inomata T, Nakamura M, Iwagami M, Midorikawa-Inomata A, Sung J, Fujimoto K, Okumura Y, Eguchi A, Iwata N, Miura M, Fujio K, Nagino K, Hori S, Tsubota K, Dana R, Murakami A. Stratification of Individual Symptoms of Contact Lens-Associated Dry Eye Using the iPhone App DryEyeRhythm: Crowdsourced Cross-Sectional Study. Journal of Medical Internet Research. 2020,22,e18996. (Journal of Medical Internet Research, IF: 5.8)
5. Eguchi A, Inomata T, Nakamura M, Nagino K, Iwagami M, Sung J, Midorikawa-Inomata A, Okumura Y, Fujio K, Fujimoto K, Miura M, Akasaki Y, Shokirova H, Hirosawa K, Kuwahara M, Zhu J, Dana R, Murakami A, Kobayashi H. Heterogeneity of eye drop use among symptomatic dry eye individuals in Japan: large-scale crowdsourced research using DryEyeRhythm application. Japanese Journal of Ophthalmology. (Japanese Journal of Ophthalmology, IF: 2.1)
6. Inomata T, Nakamura M, Sung J, Midorikawa-Inomata A, Iwagami M, Fujio K, Akasaki Y, Okumura Y, Fujimoto K, Eguchi A, Miura M, Nagino K, Shokirova H, Zhu J, Kuwahara M, Hirosawa K, Dana R, Murakami A. Smartphone-based digital phenotyping for dry eye toward P4 medicine: a crowdsourced cross-sectional study. NPJ Digit Med. 2021,4,171. (NPJ Digital Medicine, IF: 12.4)
7. Okumura Y, Inomata T, Midorikawa-Inomata A, Sung J, Fujio K, Akasaki Y, Nakamura M, Iwagami M, Fujimoto K, Eguchi A, Miura M, Nagino K, Hirosawa K, Huang T, Kuwahara M, Dana R, Murakami A. DryEyeRhythm: A reliable and valid smartphone application for the diagnosis assistance of dry eye. Ocul Surf. 2022,25,19-25. (Ocular Surface, IF: 5.9)
8. Inomata T, Sung J, Yee A, Murakami A, Okumura Y, Nagino K, Fujio K, Akasaki Y, Midorikawa-Inomata A, Eguchi A, Fujimoto K, Huang T, Morooka Y, Miura M, Shokirova H, Hirosawa K, Ohno M, Kobayashi H. P4 Medicine for Heterogeneity of Dry Eye: A Mobile Health-based Digital Cohort Study. Juntendo Iji Zasshi. 2023,69,2-13. (Juntendo Medical Journal, IF: 0)
9. Nagino K, Okumura Y, Yamaguchi M, Sung J, Nagao M, Fujio K, Akasaki Y, Huang T, Hirosawa K, Iwagami M, Midorikawa-Inomata A, Fujimoto K, Eguchi A, Okajima Y, Kakisu K, Tei Y, Yamaguchi T, Tomida D, Fukui M, Yagi-Yaguchi Y, Hori Y, Shimazaki J, Nojiri S, Morooka Y, Yee A, Miura M, Ohno M, Inomata T. Diagnostic Ability of a Smartphone App for Dry Eye Disease: Protocol for a Multicenter, Open-Label, Prospective, and Cross-sectional Study. JMIR Res Protoc. 2023,12,e45218. (JMIR Research Protocols, IF: 1.4)
10. Nagino K, Okumura Y, Akasaki Y, Fujio K, Huang T, Sung J, Midorikawa-Inomata A, Fujimoto K, Eguchi A, Hurramhon S, Yee A, Miura M, Ohno M, Hirosawa K, Morooka Y, Murakami A, Kobayashi H, Inomata T. Smartphone App-Based and Paper-Based Patient-Reported Outcomes Using a Disease-Specific Questionnaire for Dry Eye Disease: Randomized Crossover Equivalence Study. Journal of Medical Internet Research. 2023,25,e42638. (Journal of Medical Internet Research, IF: 5.8)
11. Fujio K, Nagino K, Huang T, Sung J, Akasaki Y, Okumura Y, Midorikawa-Inomata A, Fujimoto K, Eguchi A, Miura M, Hurramhon S, Yee A, Hirosawa K, Ohno M, Morooka Y, Murakami A, Kobayashi H, Inomata T. Clinical utility of maximum blink interval measured by smartphone application DryEyeRhythm to support dry eye disease diagnosis. Scientific Reports. 2023,13,13583. (Scientific Reports, IF: 3.8)
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